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Periurethral bulking agents, including collagen injections, have a long history of use in incontinence.
They have been effective in improving stress incontinence symptoms, but problems with agent migration or absorption have limited their long-term efficacy.
Although the efficacy of periurethral injection therapy is better in women than in men, the treatment does not produce lasting cure, for the same reasons.
Duloxetine is a serotonin and norepinephrine reuptake inhibitor that is indicated for depression and has been shown to increase resting urethral pressure and may, therefore, decrease stress incontinence in women.
For women with intrinsic sphincteric dysfunction, estrogen therapy, alpha agonists, or both have provided some improvement in symptoms.
Periurethral collagen injections are most effective for women with intrinsic sphincteric dysfunction, producing cure rates that last as long as 1 or 2 years.
In fact Prelude is so human like that you might bump into her avatars in Second Life and not even know."his programme induced a dialogue more human than any other I've seen" - Turing's biographer Andrew Hodges (author of Alan Turing: the Enigma) in "The Turing Test in practice"."one of the funniest experiments ever performed in computer science ..it is a small milestone in human history to have produced a machine that can do this." - Andrew Brown in The Darwin Wars. When I was an undergraduate in 1989 I hooked up an Artificial Intelligence "chatbot" called "MGonz" to the Internet, with interesting results.For many years I told people about it, and there was always a certain amount of interest.
No known reliable medical therapy exists for postprostatectomy male stress incontinence.